Lung sound analysis helps localize airway inflammation in patients with bronchial asthma

Airway inflammation can be detected by lung sound analysis (LSA) at a single point in the posterior lower lung field. We performed LSA at 7 points to examine whether the technique could identify the location of airway inflammation in patients with asthma. Breath sounds were recorded at 7 points on t...

Full description

Saved in:
Bibliographic Details
Published in:Journal of asthma and allergy 2017-01, Vol.10, p.99-108
Main Authors: Shimoda, Terufumi, Obase, Yasushi, Nagasaka, Yukio, Nakano, Hiroshi, Ishimatsu, Akiko, Kishikawa, Reiko, Iwanaga, Tomoaki
Format: Article
Language:English
Subjects:
7-point analysis
Airway management
airway obstruction
Analysis
Asthma
Asthmatic persons
Care and treatment
Chronic obstructive pulmonary disease
Diagnosis
Digitization
expiration sound presure level
expiration-to-inspiration sound pressure ratio
Family medical history
Health aspects
Hospitals
Inflammation
inspiration sound pressure level
Lungs
Nitric oxide
Original Research
Pressure
Respiratory sounds
Respiratory tract
Respiratory tract diseases
Sound
Trachea
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Airway inflammation can be detected by lung sound analysis (LSA) at a single point in the posterior lower lung field. We performed LSA at 7 points to examine whether the technique could identify the location of airway inflammation in patients with asthma. Breath sounds were recorded at 7 points on the body surface of 22 asthmatic subjects. Inspiration sound pressure level ( ), expiration sound pressure level ( ), and the expiration-to-inspiration sound pressure ratio ( ) were calculated in 6 frequency bands. The data were analyzed for potential correlation with spirometry, airway hyperresponsiveness (PC ), and fractional exhaled nitric oxide (FeNO). The data in the frequency range of 100-400 Hz ( low frequency [LF], mid frequency [MF]) were better correlated with the spirometry, PC , and FeNO values than were the or data. The left anterior chest and left posterior lower recording positions were associated with the best correlations (forced expiratory volume in 1 second/forced vital capacity: =-0.55 and =-0.58; logPC : =-0.46 and =-0.45; and FeNO: =0.42 and =0.46, respectively). The majority of asthmatic subjects with FeNO ≥70 ppb exhibited high MF levels in all lung fields (excluding the trachea) and %pred
ISSN:1178-6965
1178-6965
DOI:10.2147/JAA.S125938