Relationship between quantitative magnetic resonance imaging and clinical symptoms in patients with knee osteoarthritis

To the Editor: Quantitative magnetic resonance imaging (MRI) objectively evaluates the degeneration of cartilage in knee osteoarthritis (KOA) patients by measuring changes in proteoglycans, collagen fibers, and water content, thereby facilitating early clinical diagnosis and treatment. [4] Patients...

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Bibliographic Details
Published in:Chinese medical journal 2020-07, Vol.133 (14), p.1741-1743
Main Authors: Wang, Xin-Guang, Gao, Li-Xiang, Zhao, Min-Wei, Geng, Xiao, Wu, Tian-Chen, Yuan, Hui-Shu, Tian, Hua
Format: Article
Language:English
Subjects:
Arthritis
Body mass index
Cartilage
Cartilage, Articular
Colleges & universities
Correspondence
Humans
Knee
Knee Joint - diagnostic imaging
Magnetic Resonance Imaging
Osteoarthritis
Osteoarthritis, Knee - diagnostic imaging
Pain
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Summary:To the Editor: Quantitative magnetic resonance imaging (MRI) objectively evaluates the degeneration of cartilage in knee osteoarthritis (KOA) patients by measuring changes in proteoglycans, collagen fibers, and water content, thereby facilitating early clinical diagnosis and treatment. [4] Patients with knee joint pain caused by diseases other than KOA; secondary KOA; serious varus or valgus or flexion contracture; cruciate ligament tear, discoid meniscus, meniscus injury resulting in joint interlocking; and a history of knee surgery and those unable to complete the examination were excluded. [5] The T1rho values of the MFCC, LFCC, and MTPC and T2-mapping values of the MFCC and LTPC were higher in the mild and severe clinical symptoms group than in the mild clinical symptom group, suggesting patients with severe clinical symptoms may develop lateral cartilage lesions based on medial cartilage lesions. [...]quantitative MRI, particularly quantitative MRI values of the MFCC and T1rho sequence, could appropriately reflect clinical symptoms in KOA patients.
ISSN:0366-6999
2542-5641
DOI:10.1097/CM9.0000000000000879