Refractive outcome of premature infants with or without retinopathy of prematurity at 2 years of age: A prospective controlled cohort study

Abstract This study evaluated the extent to which refractive morbidity is correlated to preterm birth or retinopathy of prematurity (ROP) itself, or both, and examined the risk factors associated with refractive errors in a cohort of preterm infants with and without ROP compared with full-term infan...

Full description

Saved in:
Bibliographic Details
Published in:The Kaohsiung journal of medical sciences 2012-04, Vol.28 (4), p.204-211
Main Authors: Hsieh, Ching-ju, Liu, Jai-wen, Huang, Jen-shang, Lin, Keh-chung
Format: Article
Language:English
Subjects:
Analysis
Child, Preschool
Cohort Studies
Female
Humans
Infant
Infant, Newborn
Infant, Premature
Infants (Premature)
Internal Medicine
Laser treatment
Longitudinal profile
Male
Preterm infants
Prospective Studies
Refractive outcome
Retinopathy of prematurity
Retinopathy of Prematurity - therapy
Vision disorders in children
Citations: Items that this one cites
Items that cite this one
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract This study evaluated the extent to which refractive morbidity is correlated to preterm birth or retinopathy of prematurity (ROP) itself, or both, and examined the risk factors associated with refractive errors in a cohort of preterm infants with and without ROP compared with full-term infants. This longitudinal, prospective, controlled cohort study enrolled 109 infants, including 74 preterm and 35 full-term infants. Infants were divided into the following groups: no ROP, regressed ROP, laser-treated threshold ROP, and full-term. Cycloplegic refraction was determined at 6 and 24 months’ corrected age. Multiple regression models, analysis of variance (ANOVA) with post hoc comparisons, paired t test, and the χ2 test were used for data analysis. ROP status was highly predictive of significant refractive errors in preterm infants. Eyes with laser-treated threshold ROP had significant myopia at both ages (mean spherical equivalent [MSE] in right eye at both refractions −0.72, −1.21 diopters [D]), astigmatism (MSE −1.62, −1.80 D), and anisometropia (MSE 0.82, 1.02 D; ANOVA p  
ISSN:1607-551X
2410-8650
DOI:10.1016/j.kjms.2011.10.010