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Depressive Symptoms and Incident Heart Failure in the Jackson Heart Study: Differential Risk Among Black Men and Women

Background Associations between depression, incident heart failure (HF), and mortality are well documented in predominately White samples. Yet, there are sparse data from racial minorities, including those who are women, and depression is underrecognized and undertreated in the Black population. Thu...

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Bibliographic Details
Published in:Journal of the American Heart Association 2022-03, Vol.11 (5), p.e022514-e022514
Main Authors: Gaffey, Allison E, Cavanagh, Casey E, Rosman, Lindsey, Wang, Kaicheng, Deng, Yanhong, Sims, Mario, O'Brien, Emily C, Chamberlain, Alanna M, Mentz, Robert J, Glover, LáShauntá M, Burg, Matthew M
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Language:English
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Summary:Background Associations between depression, incident heart failure (HF), and mortality are well documented in predominately White samples. Yet, there are sparse data from racial minorities, including those who are women, and depression is underrecognized and undertreated in the Black population. Thus, we examined associations between baseline depressive symptoms, incident HF, and all-cause mortality across 10 years. Methods and Results We included Jackson Heart Study (JHS) participants with no history of HF at baseline (n=2651; 63.9% women; median age, 53 years). Cox proportional hazards models tested if the risk of incident HF or mortality differed by clinically significant depressive symptoms at baseline (Center for Epidemiological Studies-Depression scores ≥16 versus
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.121.022514