Childhood meningitis in Kuwait in the era of post pneumococcal conjugate vaccination: A multicenter study

Abstract This is a retrospective study to evaluate epidemiology and etiologies of childhood meningitis in Kuwait after the routine introduction of the pneumococcal conjugate vaccine. The data was collected from 196 patients in the period of 2010–2014. Aseptic meningitis accounted for 51% of the case...

Full description

Saved in:
Bibliographic Details
Published in:Journal of infection and public health 2017-11, Vol.10 (6), p.766-769
Main Authors: Sadeq, Hussain, Husain, Entesar H, Alkoot, Amna, Atyani, Suha, Al-fraij, Abdullah, Al-Daithan, Abdulrahman, AlSaleem, Talal, Taher, Anfal, Alenezi, May
Format: Article
Language:English
Subjects:
Child
Child, Preschool
Children
Female
Haemophilus - isolation & purification
Humans
Infant
Infant, Newborn
Infectious Disease
Internal Medicine
Kuwait
Kuwait - epidemiology
Male
Meningitis
Meningitis, Aseptic - epidemiology
Meningitis, Aseptic - etiology
Meningitis, Aseptic - mortality
Meningitis, Bacterial - epidemiology
Meningitis, Bacterial - etiology
Meningitis, Bacterial - mortality
Neisseria meningitidis - isolation & purification
Pediatric
Pneumococcal conjugate vaccine
Pneumococcal Vaccines - administration & dosage
Retrospective Studies
Streptococcus pneumoniae - isolation & purification
Survival Analysis
Vaccination - utilization
Vaccine
Vaccines, Conjugate - administration & dosage
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract This is a retrospective study to evaluate epidemiology and etiologies of childhood meningitis in Kuwait after the routine introduction of the pneumococcal conjugate vaccine. The data was collected from 196 patients in the period of 2010–2014. Aseptic meningitis accounted for 51% of the cases, bacterial meningitis accounted for 29% cases and partially treated meningitis were 20%. Organisms causing bacterial meningitis were: Streptococcus pneumoniae 40.4%, Neisseria meningitidis 17 .6%, Haemophilus spp. 12.2%, other gram positive or negative 19.3%, and Group B Streptococcus 8.8%. The hospitalization was complicated by admission to the ICU in 16.3% patients. Sequelae on discharge were seen in 4%, and 2.5% died of complications of meningitis. In children with pneumococcal meningitis, 48% were admitted to the ICU, 35% were discharged with sequelae and 13% died. In the era of post pneumococcal conjugate vaccination, S. pneumoniae remains the leading cause of bacterial meningitis with the greatest morbidity and mortality.
ISSN:1876-0341
1876-035X
DOI:10.1016/j.jiph.2016.11.009