Orthology-Based Estimate of the Contribution of Horizontal Gene Transfer from Distantly Related Bacteria to the Intraspecific Diversity and Differentiation of Xylella fastidiosa

is a xylem-limited bacterium phylogenetically related to the xanthomonads, with an unusually large and diversified range of plant hosts. To ascertain the origin of its peculiarities, its pan-genome was scanned to identify the genes that are not coherent with its phylogenetic position within the orde...

Full description

Saved in:
Bibliographic Details
Published in:Pathogens (Basel) 2021-01, Vol.10 (1), p.46
Main Authors: Firrao, Giuseppe, Scortichini, Marco, Pagliari, Laura
Format: Article
Language:English
Subjects:
Bacteria
Deoxyribonucleic acid
DNA
Environmental DNA
Enzymes
Flowers & plants
Gene transfer
Genes
Genomes
HGT
hierarchical orthologous group
Hogs
Homology
Horizontal transfer
Host plants
Orthology
pangenome
Phylogeny
Proteins
vasicola
Xanthomonadales
Xanthomonas
Xylella fastidiosa
Xylem
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:is a xylem-limited bacterium phylogenetically related to the xanthomonads, with an unusually large and diversified range of plant hosts. To ascertain the origin of its peculiarities, its pan-genome was scanned to identify the genes that are not coherent with its phylogenetic position within the order . The results of the analysis revealed that a large fraction of the genes of the pan-genome have no ortholog or close paralog in the order . For a significant part of the genes, the closest homologue was found in bacteria belonging to distantly related taxonomic groups, most frequently in the . Other species, such as and which were investigated for comparison, did not show a similar genetic contribution from distant branches of the prokaryotic tree of life. This finding indicates that the process of acquisition of DNA from the environment is still a relevant component of evolution. Although the ability of strains to recombine among themselves is well known, the results of the pan-genome analyses stressed the additional relevance of environmental DNA in shaping their genomes, with potential consequences on their phytopathological features.
ISSN:2076-0817
2076-0817
DOI:10.3390/pathogens10010046