Daily Changes in Pain, Mood and Physical Function in Youth Hospitalized for Sickle Cell Disease Pain

BACKGROUND: Youth with sickle cell disease (SCD) are commonly hospitalized for treatment of painful vaso‐occlusive episodes (VOE). However, limited data are available concerning the course of hospitalization for these children and adolescents and, in particular, whether daily changes occur in pain,...

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Bibliographic Details
Published in:Pain research & management 2013-01, Vol.18 (1), p.33-38
Main Authors: Zempsky, William T, Palermo, Tonya M, Corsi, John M, Lewandowski, Amy S, Zhou, Chuan, Casella, James F
Format: Article
Language:English
Subjects:
Hospitalization
Original
Pediatrics
Sickle cell disease
Studies
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Summary:BACKGROUND: Youth with sickle cell disease (SCD) are commonly hospitalized for treatment of painful vaso‐occlusive episodes (VOE). However, limited data are available concerning the course of hospitalization for these children and adolescents and, in particular, whether daily changes occur in pain, emotional status and physical function. OBJECTIVES: To characterize changes in daily pain intensity, physical function and mood over the course of hospitalization, and to determine whether specific clinical characteristics were associated with these changes. METHODS: Daily ratings of pain (0 to 10 numerical rating scale) and mood (Positive and Negative Affect Scale for Children) were completed by 25 youth (11 to 20 years of age) with SCD over a total of 152 days (mean [± SD] = 6.7±5.6 days) of hospitalization. Trained raters determined each youth’s daily physical function. RESULTS: Linear mixed modelling was used to examine changes in pain, mood and physical function during hospital stay. The rate of change over the course of hospitalization was significant for reductions in pain intensity (P
ISSN:1203-6765
1918-1523
DOI:10.1155/2013/487060