Two-Photon-Induced [2 + 2] Cycloaddition of Bis-thymines: A Biocompatible and Reversible Approach

Despite having great value across a wide variety of scientific fields, two-photon polymerizations currently suffer from two significant problems: the need for photoinitiators, which generate toxic side products, and the irreversibility of the process. Hence, the design of a versatile approach that c...

Full description

Saved in:
Bibliographic Details
Published in:ACS omega 2020-05, Vol.5 (20), p.11547-11552
Main Authors: Ricci, Monica, Rutten, Martin G.T.A, Toyouchi, Shuichi, Nanayakkara, Sepa, Fortuni, Beatrice, Vitale, Raffaele, Rocha, Susana, Wilson, Daniela A, Hofkens, Johan, Saito, Kei, Uji-i, Hiroshi
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Despite having great value across a wide variety of scientific fields, two-photon polymerizations currently suffer from two significant problems: the need for photoinitiators, which generate toxic side products, and the irreversibility of the process. Hence, the design of a versatile approach that circumvents these issues represents a major scientific challenge. Herein, we report a two-photon absorption strategy where reversible [2 + 2] cycloaddition of bis-thymines was achieved without the need for any photoinitiator. The cycloaddition and cycloreversion reactions could be induced by simply changing the irradiation wavelength, and repeated writing and erasing cycles were performed. The simplicity, reversibility, and biocompatibility of this strategy open up a whole new toolbox for applications across a wide variety of scientific fields.
ISSN:2470-1343
2470-1343
DOI:10.1021/acsomega.0c00770