Rapid Increase of Oral Bacteria in Nasopharyngeal Microbiota After Antibiotic Treatment in Children With Invasive Pneumococcal Disease

IntroductionAntibiotics are commonly prescribed to young children for treating bacterial infections such as invasive pneumococcal disease (IPD) caused by Streptococcus pneumoniae. Despite the obvious benefits of antibiotics, little is known about their possible side effects on children's nasoph...

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Bibliographic Details
Published in:Frontiers in cellular and infection microbiology 2021-10, Vol.11, p.744727-744727
Main Authors: Henares, Desiree, Rocafort, Muntsa, Brotons, Pedro, de Sevilla, Mariona F., Mira, Alex, Launes, Cristian, Cabrera-Rubio, Raul, Muñoz-Almagro, Carmen
Format: Article
Language:English
Subjects:
antibiotics
Cellular and Infection Microbiology
children
invasive pneumococcal disease (IPD)
nasopharyngeal microbiota
nosocomial bacteria
oral bacteria
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Summary:IntroductionAntibiotics are commonly prescribed to young children for treating bacterial infections such as invasive pneumococcal disease (IPD) caused by Streptococcus pneumoniae. Despite the obvious benefits of antibiotics, little is known about their possible side effects on children's nasopharyngeal microbiota. In other ecological niches, antibiotics have been described to perturb the balanced microbiota with short- and long-term effects on children's health. The present study aims to evaluate and compare the nasopharyngeal microbiota of children with IPD and different degree of antibiotic exposure. MethodsWe investigated differences in nasopharyngeal microbiota of two groups of children
ISSN:2235-2988
2235-2988
DOI:10.3389/fcimb.2021.744727