Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis

Dysphagia has a broad aetiology and so it is essential to identify the precise cause. Cervical cancer metastasis is distinctive in that it usually involves local lymph node invasion; however, approximately 1% of cases have mediastinal involvement, which can cause severe compressive symptoms in rare...

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Bibliographic Details
Published in:European journal of case reports in internal medicine 2022-01, Vol.9 (1), p.003136-003136
Main Authors: Singh, Vinit, Gor, Dhairya, Azad, Sarah, Ricca, Anthony, Xu, Yiqing, Meghal, Trishala
Format: Article
Language:English
Subjects:
cervical cancer
dysphagia
mediastinal lymph node
metastasis
oesophagus
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Summary:Dysphagia has a broad aetiology and so it is essential to identify the precise cause. Cervical cancer metastasis is distinctive in that it usually involves local lymph node invasion; however, approximately 1% of cases have mediastinal involvement, which can cause severe compressive symptoms in rare situations. To highlight an uncommon severe manifestation of cervical cancer relapse, we describe a case of dysphagia in a woman with a history of cervical cancer. After a thorough investigation that included endoscopy, endoscopy with ultrasound, an oesophagogram and fine needle aspiration, we eventually reached the diagnosis of mediastinal metastatic cervical cancer. Following interventions, the patient's condition gradually improved, both clinically and radiographically. Mediastinal lymph node enlargement causing dysphagia can be a presenting sign of a metastatic lesion from treated cervical cancer.A PEG tube is helpful in relieving dysphagia caused by metastatic mediastinal lymph node enlargement and as bridge for nutrition during chemotherapy.The VEGF inhibitor bevacizumab can be used in advanced metastatic cervical cancer.Check-point inhibitors like pembrolizumab can be used in metastatic cervical cancer.
ISSN:2284-2594
2284-2594
DOI:10.12890/2022_003136