Utility of accumulated opioid supply days and individual patient factors in predicting probability of transitioning to long‐term opioid use: An observational study in the Veterans Health Administration

Initial supply days dispensed to new users is strongly predictive of future long‐term opioid use (LTO). The objective was to examine whether a model integrating additional clinical variables conferred meaningful improvement in predicting LTO, beyond a simple approach using only accumulated supply. T...

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Bibliographic Details
Published in:Pharmacology research & perspectives 2020-04, Vol.8 (2), p.e00571-n/a
Main Authors: Hadlandsmyth, Katherine, Mosher, Hilary J., Vander Weg, Mark W., O’Shea, Amy M., McCoy, Kimberly D., Lund, Brian C.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Analgesics, Opioid - administration & dosage
Analgesics, Opioid - supply & distribution
Drug Prescriptions - statistics & numerical data
Drug Utilization
Female
Humans
Intervention
long‐term
Male
medical record data
Middle Aged
Narcotics
Observational studies
opioid
Opioid-Related Disorders
Original
Patients
Pharmacology
Prescriptions
Risk
Time Factors
United States
United States Department of Veterans Affairs - statistics & numerical data
Variables
Veteran
Veterans Health
Young Adult
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Summary:Initial supply days dispensed to new users is strongly predictive of future long‐term opioid use (LTO). The objective was to examine whether a model integrating additional clinical variables conferred meaningful improvement in predicting LTO, beyond a simple approach using only accumulated supply. Three cohorts were created using Veteran's Health Administration data based on accumulated supply days during the 90 days following opioid initiation: (a)
ISSN:2052-1707
2052-1707
DOI:10.1002/prp2.571