HIV/AIDS patients undergoing total knee arthroplasty are at higher risk of acute renal failure and transfusion and incurred higher cost: a propensity-matched database study

• Published in: Knee surgery & related research 2022-06, Vol.34 (1), p.28-28, Article 28
• Main Authors: Sakthivelnathan, Vishaal, Senthil, Tejas, Varatharaj, Sushrruti, Mounasamy, Varatharaj, Sambandam, Senthil
• Format: Article
• Language: English
• Subjects: Acquired immune deficiency syndrome; AIDS; Blood transfusions; HIV; Human immunodeficiency virus; Surgical outcomes; Total knee arthroplasty
• ISSN: 2234-0726; 2234-2451; 2234-2451
• DOI: 10.1186/s43019-022-00156-0

Human immunodeficiency virus (HIV) is a retrovirus that can cause acquired immunodeficiency syndrome (AIDS). Total knee arthroplasty (TKA) in HIV-positive patients has not been well documented in the current literature. Thus, this study aimed to examine the early postoperative outcomes and complications of HIV-positive TKA patients as compared to TKA patients who are HIV-negative patients by utilizing the National Inpatient Sample (NIS) database. Admissions data for TKA and HIV were analyzed from the NIS database using ICD-10-CM diagnosis codes. An extensive array of preoperative and postoperative variables was compared among HIV positive TKA patients and HIV negative TKA patients. An unmatched analysis and a matched analysis using a 1:1 propensity match algorithm were conducted to compare the two groups. The average age of the HIV-positive group was lower than the HIV-negative group (59.0 vs 66.7, p