Phytogenic Compounds Supplemented to Gestating Hyperprolific Sows Affects the Gut Health-Related Gene Expression and Histological Responses in Neonate Piglets

This research aims to determine whether a specific blend of phytogenic compounds (BPC) supplemented in gestating hyperprolific sow diets can promote prenatal maternal effects in terms of piglet gut function and morphology. Twenty-eight (Landrace × Yorkshire) gilts and sows (parity 0 to 7) were rando...

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Bibliographic Details
Published in:Frontiers in veterinary science 2021-06, Vol.8, p.639719-639719
Main Authors: Reyes-Camacho, David, Pérez, José Francisco, Vinyeta, Ester, Aumiller, Tobias, Criado-Mesas, Lourdes, Folch, Josep Maria, Van der Klis, Jan Dirk, Solà-Oriol, David
Format: Article
Language:English
Subjects:
hyperprolific sows
neonatal programming
phytogenic compounds
piglet gut health
prenatal exposure
Veterinary Science
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Summary:This research aims to determine whether a specific blend of phytogenic compounds (BPC) supplemented in gestating hyperprolific sow diets can promote prenatal maternal effects in terms of piglet gut function and morphology. Twenty-eight (Landrace × Yorkshire) gilts and sows (parity 0 to 7) were randomly distributed by parity number and body weight into two dietary treatments: unsupplemented Control (CON) ( n = 14) or CON diet supplemented with 1 g/kg feed of BPC during gestation ( n = 14). The BPC supplementation during gestation of sows downregulated the neonate piglets' jejunal genes involved in oxidation ( SOD2 ) and nutrient transport ( SLC16A1/MCT1, SLC11A2/DMT1 , and SLC39A/ZIP4 ), while IFNG and CLDN4 related to immune response and barrier function, respectively, were upregulated ( q < 0.10). In addition, the jejunal villus height and the ratio of the villus height to crypt depth tended to increase ( p < 0.10), while goblet cell volume density was higher ( p < 0.05) in BPC compared to CON. In conclusion, dietary supplementation of BPC in gestating diets for hyperprolific sows influences neonatal histomorphology and expression of genes related to the intestinal function and health.
ISSN:2297-1769
2297-1769
DOI:10.3389/fvets.2021.639719