Protein engineering and iterative multimodule optimization for vitamin B6 production in Escherichia coli

Vitamin B 6 is an essential nutrient with extensive applications in the medicine, food, animal feed, and cosmetics industries. Pyridoxine (PN), the most common commercial form of vitamin B 6 , is currently chemically synthesized using expensive and toxic chemicals. However, the low catalytic efficie...

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Bibliographic Details
Published in:Nature communications 2023-08, Vol.14 (1), p.5304-16, Article 5304
Main Authors: Liu, Linxia, Li, Jinlong, Gai, Yuanming, Tian, Zhizhong, Wang, Yanyan, Wang, Tenghe, Liu, Pi, Yuan, Qianqian, Ma, Hongwu, Lee, Sang Yup, Zhang, Dawei
Format: Article
Language:English
Subjects:
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Animal feed
Batch culture
Cosmetics
E coli
Engineering
Enzymes
Escherichia coli
Feeds
Fermentation
Humanities and Social Sciences
Metabolic pathways
Metabolism
Microorganisms
multidisciplinary
Optimization
Protein engineering
Proteins
Pyridoxine
Science
Science (multidisciplinary)
Vitamin B6
Vitamins
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