The Contemporary Role of Salvage Radical Prostatectomy in the Management of Recurrent Prostate Cancer: An Up-to-Date Review

Prostate cancer is the second most common cancer among men, with many treatment modalities available for patients, such as radical prostatectomy, external beam radiotherapy, brachytherapy, high-intensity focused ultrasound, cryotherapy, electroporation and other whole-gland or focal ablative novel t...

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Published in:Life (Basel, Switzerland) Switzerland), 2024-07, Vol.14 (7), p.868
Main Authors: Katsimperis, Stamatios, Pinitas, Alexandros, Zerva, Maria, Bellos, Themistoklis, Manolitsis, Ioannis, Feretzakis, Georgios, Verykios, Vassilios S, Kyriazis, Ioannis, Neofytou, Panagiotis, Kapsalos, Sotirios, Deligiannis, Panagiotis, Triantafyllou, Panagiotis, Juliebø-Jones, Patrick, Somani, Bhaskar, Mitsogiannis, Iraklis, Tzelves, Lazaros
Format: Article
Language:English
Subjects:
Ablation
Biopsy
Brachytherapy
Cancer therapies
Cryotherapy
Disease management
Dissection
Electroporation
Literature reviews
Metastasis
Prostate cancer
Prostatectomy
Radiation therapy
recurrence
robotic prostatectomy
Robotic surgery
salvage radical prostatectomy
salvage therapy
Surgeons
Surgical outcomes
Tomography
Ultrasonic imaging
Ultrasonic testing
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Summary:Prostate cancer is the second most common cancer among men, with many treatment modalities available for patients, such as radical prostatectomy, external beam radiotherapy, brachytherapy, high-intensity focused ultrasound, cryotherapy, electroporation and other whole-gland or focal ablative novel techniques. Unfortunately, up to 60% of men with prostate cancer experience recurrence at 5 to 10 years. Salvage radical prostatectomy can be offered as an option in the setting of recurrence after a primary non-surgical treatment. However, the complexity of salvage radical prostatectomy is considered to be greater than that of primary surgery, making it the least popular treatment of choice. With the wide use of robotic platforms in urologic oncologic surgery, salvage radical prostatectomy has attracted attention again because, compared to past data, modern series involving salvage Robot-Assisted Radical Prostatectomy have shown promising results. In this narrative literature review, we comprehensively examined data on salvage radical prostatectomy. We investigated the correlation between the different types of primary prostate cancer therapy and the following salvage radical prostatectomy. Furthermore, we explored the concept of a robotic approach and its beneficial effect in salvage surgery. Lastly, we emphasized several promising avenues for future research in this field.
ISSN:2075-1729
2075-1729
DOI:10.3390/life14070868