Ultra-Widefield Fluorescein Angiography Image Brightness Compensation Based on Geometrical Features

Ultra-widefield fluorescein angiography (UWFA) is an emerging imaging modality used to characterise pathologies in the retinal vasculature, such as microaneurysms (MAs) and vascular leakages. Despite its potential value for diagnosis and disease screening, objective quantitative assessment of retina...

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Bibliographic Details
Published in:Sensors (Basel, Switzerland) Switzerland), 2021-12, Vol.22 (1), p.12
Main Authors: Więcławek, Wojciech, Danch-Wierzchowska, Marta, Rudzki, Marcin, Sędziak-Marcinek, Bogumiła, Teper, Slawomir Jan
Format: Article
Language:English
Subjects:
Algorithms
Angiography
Brightness
curve length
Diabetes
Diabetic retinopathy
Fluorescein
Fluorescein Angiography
gamma correction
Image analysis
image enhancement
Image quality
Imaging techniques
Medical imaging
Methods
Pilot Projects
Retina
Retinal Vessels
solid angle
UWFA
Visual Acuity
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Summary:Ultra-widefield fluorescein angiography (UWFA) is an emerging imaging modality used to characterise pathologies in the retinal vasculature, such as microaneurysms (MAs) and vascular leakages. Despite its potential value for diagnosis and disease screening, objective quantitative assessment of retinal pathologies by UWFA is currently limited because laborious manual processing is required. In this report, we describe a geometrical method for uneven brightness compensation inherent to UWFA imaging technique. The correction function is based on the geometrical eyeball shape, therefore it is fully automated and depends only on pixel distance from the center of the imaged retina. The method's performance was assessed on a database containing 256 UWFA images with the use of several image quality measures that show the correction method improves image quality. The method is also compared to the commonly used CLAHE approach and was also employed in a pilot study for vascular segmentation, giving a noticeable improvement in segmentation results. Therefore, the method can be used as an image preprocessing step in retinal UWFA image analysis.
ISSN:1424-8220
1424-8220
DOI:10.3390/s22010012