Hypothyroidism Is Associated With Longer Hospital Stay Following Implantation Of Left Ventricular Assist Device

• Published in: Clinical Medicine Insights. Cardiology 2021-12, Vol.15, p.11795468211058761-11795468211058761
• Main Authors: Isa, Sakiru O, Buhari, Olajide, Adeniran-Isa, Muminat, Baral, Nischit, Adhikari, Govinda, AbdulAzeem, Basel, Savarapu, Pramod, Adekolujo, Oyebimpe, Hassan, Mustafa, Adeboye, Adedayo
• Format: Article
• Language: English
• Subjects: Heart failure; Hypothyroidism; Kidneys; Original
• ISSN: 1179-5468; 1179-5468
• DOI: 10.1177/11795468211058761

Background: There has been a steady and consistent rise in the use of left ventricular assist devices in the management of patients with advanced heart failure. Hypothyroidism also remains one of the most common endocrine conditions with a significant impact on the development and overall outcomes of heart failure. The authors analyzed the National Inpatient Sample to evaluate the effect of hypothyroidism on the in-hospital outcomes of patients with end-stage heart failure following the placement of left ventricular assist device. Methods: The national inpatient sample was queried to identify all adult patients who had LVAD placement from 2004 to 2014. They were subsequently divided into those with hypothyroidism and those without hypothyroidism. The primary outcome was in-hospital mortality. Other outcomes were acute kidney injury, length, and cost of hospitalization. Logistic regression models were created to determine the outcomes of interest. Results: Of 2643 patients in the study, 5.4% had hypothyroidism, and 94.6% did not. The hypothyroid patients were significantly older compared to the non-hypothyroid patients (mean age 58.6 years vs 49.95 years, P-value