Acute respiratory distress syndrome due to inhalation of acryloyl chloride

Background Acryloyl chloride is a highly toxic volatile liquid that can cause pulmonary edema. However, no sufficient treatment reports have been published to date. Here, we report a case of acute respiratory distress syndrome (ARDS) caused by acryloyl chloride inhalation. Case presentation The pati...

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Bibliographic Details
Published in:Acute medicine & surgery 2022-01, Vol.9 (1), p.e724-n/a
Main Authors: Shima, Takafumi, Kashiwagi, Hideki, Ino, Haruka, Tanaka, Suguru, Fukuda, Makiko, Kobata, Hitoshi
Format: Article
Language:English
Subjects:
Acryloyl chloride
acute respiratory distress syndrome
Blood
Body temperature
Case Report
Chloride
Gases
high‐flow nasal cannula
Hospitalization
Hydrochloric acid
hydrogen chloride
Intensive care
Intubation
Mortality
Patients
phosgene
Radiography
Respiratory distress syndrome
Sodium
Steroids
Tomography
Ventilators
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Summary:Background Acryloyl chloride is a highly toxic volatile liquid that can cause pulmonary edema. However, no sufficient treatment reports have been published to date. Here, we report a case of acute respiratory distress syndrome (ARDS) caused by acryloyl chloride inhalation. Case presentation The patient was a 36‐year‐old man with accidental exposure to acryloyl chloride. The patient had dyspnea and wet cough, with approximately 88% percutaneous oxygen saturation at room air. He was diagnosed with ARDS and admitted to the intensive care unit. Initially, he was treated with a high‐flow nasal cannula and sivelestat sodium. However, due to the possibility of delayed exacerbation, the patient was switched to methylprednisolone. Oxygenation gradually improved, and the patient was discharged on the day 8 of hospitalization. Conclusion We report the case of a patient who developed ARDS with delayed exacerbation after the inhalation of acryloyl chloride, which was treated without endotracheal intubation. Acryloyl chloride is a highly toxic volatile liquid that can cause pulmonary edema. We report the case of a patient who developed acute respiratory distress syndrome with delayed exacerbation after the inhalation of acryloyl chloride, which was treated without endotracheal intubation.
ISSN:2052-8817
2052-8817
DOI:10.1002/ams2.724