meaning of early percutaneous coronary intervention in acute coronary syndrome with preserved ST elevation

• Published in: Central European journal of medicine 2009-09, Vol.4 (3), p.265-271
• Main Authors: Wierzbicka, Magdalena, Kośmider, Maciej, Bielecka-Dąbrowa, Agata, Goch, Jan Henryk
• Format: Article
• Language: English
• Subjects: Biomedicine; Cardiogenic shock; Internal Medicine; Maternal and Child Health; Medicine; Medicine & Public Health; Percutaneous coronary intervention; Reproductive Medicine; Research Article; Surgery; Time to treatment
• ISSN: 1895-1058; 2391-5463; 1644-3640; 2391-5463
• DOI: 10.2478/s11536-009-0042-5

To determine if delaying the primary precutaneous coronary intervention (PCI) for >6 hours for acute coronary syndrome with preserved ST elevation (STE-ACS) affects the PCI angiography effectiveness and clinical prognosis. The PCI was performed: for 71% of patients 6h from the beginning of pain (group 2). For 1% of patients from group 1 and 3.4% of patients from group 2, no passage has been opened in the artery after STE-ACS. In spite of opening the passage mechanically, the phenomenon of lack of tissue reflow occurred in 2.7% of patients from group 1 and 12% of patients from group 2. Dangerous ventricular arrhythmias occurred more frequently in patients from group 2, including VF, asystole, haemodynamic complications classed 4° according to the Killip-Kimball scale and death. In an univariate logistic regression analysis, the following risk factors for death during the hospital phase were identified: delayed PCI >6 hours, 4° haemodynamic complications according to the Killip-Kimball scale, LVEF