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Relevance of heat stress and dehydration to chronic kidney disease (CKDu) in Sri Lanka

AbstractChronic kidney disease in the absence of hypertension and diabetes is a growing problem among agricultural laborers in tropical and subtropical regions. It is unclear if heat stress and dehydration are risk factors for this form of chronic kidney disease (CKDu). To investigate this relations...

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Published in:Preventive medicine reports 2019-09, Vol.15, p.100928-100928, Article 100928
Main Authors: Jayasekara, K.B, Kulasooriya, P.N, Wijayasiri, K.N, Rajapakse, E.D, Dulshika, D.S, Bandara, Palitha, Fried, L.F, De Silva, A, Albert, S.M
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Language:English
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Summary:AbstractChronic kidney disease in the absence of hypertension and diabetes is a growing problem among agricultural laborers in tropical and subtropical regions. It is unclear if heat stress and dehydration are risk factors for this form of chronic kidney disease (CKDu). To investigate this relationship, agricultural workers in four villages (n = 261) in North Central Province, Sri Lanka completed the US National Institute for Occupational Safety and Health (NIOSH) health hazard evaluation of heat stress, translated into Sinhalese (July 2017). We constructed a heat stress/dehydration index based on the frequency of 16 symptoms (range 0–32; reliability, 0.84). Workers provided a urine sample for dipstick assessment of urine albumin-creatinine ratio (ACR) and refractometer analysis of urine concentration. Of 261 respondents, 41 participants reported diabetes or chronic kidney disease. They scored higher on the heat stress-dehydration index (10.78 vs. 8.03, p  30 (85.4% vs. 69.4%, p 
ISSN:2211-3355
2211-3355
DOI:10.1016/j.pmedr.2019.100928