Ketamine versus propofol for strabismus surgery in children

• Published in: Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2010-01, Vol.4 (default), p.673-679
• Main Authors: Mizrak, Ayse, Erbagci, Ibrahim, Arici, Tulin, Ozcan, Ibrahim, Ganidagli, Suleyman, Tatar, Gurkan, Oner, Unsal
• Format: Article
• Language: English
• Subjects: Agitation; Anesthetics; Children; Infusion; Ketamine; Ophthalmology; Original Research; Patients; pediatrics; propofol; Reflexes; strabismus; Surgery
• ISSN: 1177-5483; 1177-5467; 1177-5483
• DOI: 10.2147/OPTH.S11336

To compare the effects of intravenous infusion of ketamine and propofol anesthesia in children undergoing strabismus surgery. Sixty pediatric patients aged 4-11 years were enrolled for the study. Patients in Group K were infused ketamine 1-3 mg/kg/hr (n = 30) and patients in Group P were infused with propofol 6-9 mg/kg/hr (n = 30). After giving fentanyl 1 mug/kg and rocuronium bromide 0.5 mg/kg, patients were intubated. The consumption of anesthetics (P = 0.0001) and antiemetics (P = 0.004), the incidence of oculocardiac reflex (P = 0.02) in Group K were significantly lower than in Group P. The recovery time (P = 0.008), postoperative agitation score (P = 0.005), Face Pain Scale (P = 0.001), Ramsay Sedation Score (P = 0.01) during awakening and at postoperative 30th min (P = 0.02) in Group K were significantly lower than in Group P. The postoperative agitation score during awakening was significantly lower than the preoperative values in Group K (P = 0.0001). The infusion of ketamine is more advantageous than the infusion of propofol in children for use in strabismus surgery.