Comparison of changes in pulse wave velocity in patients on peritoneal dialysis and hemodialysis

• Published in: Saudi journal of kidney diseases and transplantation 2021-03, Vol.32 (2), p.336-340
• Main Authors: Barrah, Sana, Kheder, Rania, Jebali, Hela, Krid, Madiha, Smaoui, Wided, Beji, Soumaya, Hmida, Fathi, Fatma, Lilia, Zouaghi, Mohamed
• Format: Article
• Language: English
• Subjects: Adult; Analysis; Antihypertensive Agents - adverse effects; Arteries - physiopathology; Cardiovascular diseases; Chronic kidney failure; Female; Hemodialysis; Humans; Hypertension - drug therapy; Kidney Failure, Chronic - complications; Kidney Failure, Chronic - diagnosis; Kidney Failure, Chronic - therapy; Male; Metabolic disorders; Middle Aged; Mortality; Peritoneal dialysis; Peritoneal Dialysis - adverse effects; Prognosis; Pulse Wave Analysis; Renal Dialysis - adverse effects; Vascular Stiffness - drug effects
• ISSN: 1319-2442; 2320-3838
• DOI: 10.4103/1319-2442.335444

Cardiovascular disease is the leading cause of death of dialyzed patients. Aortic stiffness, evaluated by the carotid-femoral pulse wave velocity (cfPWV), is now considered as a prognostic factor for cardiovascular mortality in patients with chronic kidney diseases. The peritoneal dialysis (PD) patients had significantly stiffer arteries. cfPWV was 9.12 ± 2.7 m/s in PD patients without significant correlation compared to hemodialysis (HD) patients (8.97 ± 2.52 m/s). In the univariate study, we found a statistically significant correlation between PWV and age (P = 0), between the pulse wave velocity and phosphorus (P = 0.46), between the VOP and PTH (P = 0.013) and between PWV and dyslipidemia (P = 0.014). Other variables such as phospho-calcic product, hemoglobin, total cholesterol, and KT/V were not significant. To identify the risk factors independently linked to the event, we conducted a multi-varied analysis. A correlation was found between VOP and dyslipidemia (P = 0.008). The other variables were insignificant.