Enhanced specific loss power of hematite–chitosan nanohybrid synthesized by hydrothermal method

• Published in: Royal Society open science 2023-10, Vol.10 (10), p.230384-230384
• Main Authors: Deb, Nandita, Rashid, Rimi, Das, H., Syed, Ishtiaque M., Hoque, S. Manjura
• Format: Article
• Language: English
• Subjects: Chemistry; hematite; HRTEM; hyperthermia; magnetization; morin transition
• ISSN: 2054-5703; 2054-5703
• DOI: 10.1098/rsos.230384

We used a hydrothermal technique to develop nano-scale α-Fe 2 O 3 particles and functionalized them with chitosan. An X-ray diffraction study revealed α-Fe 2 O 3 nanoparticles were of single-phase, lattice constants were a = 5.07 Å and c = 13.68 Å, and the grain size was 27 nm. The presence of lattice fringes in the HRTEM image confirmed the crystalline nature of the α-Fe 2 O 3 . The Mössbauer spectra reveal a mixed relaxation state, which supports the PPMS studies. Zero-field cooled studies revealed the existence of a Morin transition and blocking temperature. The z-average value of the coated particles by DLS was between 218 and 235 nm, PDI ranged from 0.048 to 0.119, and zeta potential was +46.8 mV. We incubated the Vero and HeLa cell lines for 24 h to study the viability of the nanohybrids at different concentrations. Hyperthermia studies revealed the maximum temperature and specific loss power attained by the hematite–chitosan nanohybrid solution of a concentration between 0.25–4 mg ml −1 . The T max at the lowest and highest concentrations of 0.25 and 4 mg ml −1 were 42.9 and 48.3°C, while the SLP were 501.6 and 35.5 W g −1 , which are remarkably high when the maximum magnetization of α-Fe 2 O 3 nanoparticles was as small as 1.98 emu g −1 at 300 K.