Addition of gadolinium contrast to three-dimensional SSFP MR sequences improves the visibility of coronary artery anatomy in young children

This study aims to compare the value of a gadolinium contrast-enhanced 1.5-T three-dimensional (3D) steady-state free precession (SSFP) sequence with that of a noncontrast 3D SSFP sequence for magnetic resonance coronary angiography in a pediatric population. Seventy-nine patients from 1 month to 18...

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Bibliographic Details
Published in:Frontiers in pediatrics 2023-05, Vol.11, p.1159347-1159347
Main Authors: Shen, Quanli, Lin, Chengxiang, Yao, Qiong, Wang, Junbo, Zhou, Jian, He, Lan, Chen, Gang, Hu, Xihong
Format: Article
Language:English
Subjects:
children
contrast media
magnetic resonance coronary angiography
Pediatrics
steady-state free precession
whole heart
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Summary:This study aims to compare the value of a gadolinium contrast-enhanced 1.5-T three-dimensional (3D) steady-state free precession (SSFP) sequence with that of a noncontrast 3D SSFP sequence for magnetic resonance coronary angiography in a pediatric population. Seventy-nine patients from 1 month to 18 years old participated in this study. A 3D SSFP coronary MRA at 1.5-T was applied before and after gadolinium-diethylenetriaminepentaaceticacid (DTPA) injection. The detection rates of coronary arteries and side branches were assessed by McNemar's test. The image quality, vessel length, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) of the coronary arteries were analyzed by the Wilcoxon signed-rank test. The intra- and interobserver agreements were evaluated with a weighted kappa test or an intraclass correlation efficient test. A contrast-enhanced scan detected more coronary arteries than a noncontrast-enhanced scan in patients under 2 years old (  
ISSN:2296-2360
2296-2360
DOI:10.3389/fped.2023.1159347