High-throughput screening identifies broad-spectrum Coronavirus entry inhibitors

The COVID-19 pandemic highlighted the need for antivirals against emerging coronaviruses (CoV). Inhibiting spike (S) glycoprotein-mediated viral entry is a promising strategy. To identify small molecule inhibitors that block entry downstream of receptor binding, we established a high-throughput scre...

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Published in:iScience 2024-06, Vol.27 (6), p.110019, Article 110019
Main Authors: Khan, Suman, Partuk, Efrat Ozer, Chiaravalli, Jeanne, Kozer, Noga, Shurrush, Khriesto A., Elbaz-Alon, Yael, Scher, Nadav, Giraud, Emilie, Tran-Rajau, Jaouen, Agou, Fabrice, Barr, Haim Michael, Avinoam, Ori
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Language:English
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