Elevated urinary monocyte chemoattractant protein-1 levels in children with Henoch-Schonlein purpura nephritis

Chemokine monocyte chemoattractant protein-1 (MCP-1) has been proved as a potential urinary biomarker in nephropathies. The aim of this study was to investigate the urinary monocyte chemoattractant protein-1 (MCP-1) levels and clinical significance in Henoch-Schonlein purpura (HSP) children with and...

Full description

Saved in:
Bibliographic Details
Published in:Pediatrics and neonatology 2018-06, Vol.59 (3), p.238-243
Main Authors: Wang, Jiapei, Ying, Qianqian, Zhong, Shiling, Chen, Yuanling, Di, Yazhen, Dai, Xiahua, Zheng, Jika, Shen, Mengjiao
Format: Article
Language:English
Subjects:
children
Henoch-Schonlein purpura nephritis
monocyte chemoattractant protein-1
proteinuria
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Chemokine monocyte chemoattractant protein-1 (MCP-1) has been proved as a potential urinary biomarker in nephropathies. The aim of this study was to investigate the urinary monocyte chemoattractant protein-1 (MCP-1) levels and clinical significance in Henoch-Schonlein purpura (HSP) children with and without nephritis and determine the association of MCP-1 with proteinuria. Methods: A total of 261 HSP children—with or without nephritis—and 84 healthy control children were enrolled in this study. Of these, 126 HSP nephritis (HSPN) children were subdivided into three groups according to total urine protein in 24 h (TUP): Group A, mild proteinuria group with TUP
ISSN:1875-9572
DOI:10.1016/j.pedneo.2017.08.008