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The oxanorbornene approach to 3-hydroxy, 3,4-dihydroxy and 3,4,5-trihydroxy derivatives of 2-aminocyclohexanecarboxylic acid

The nitro oxanorbornene adduct derived from the Diels-Alder reaction of ethyl (E)-3-nitroacrylate and furan provides a versatile template for the stereoselective synthesis of hydroxylated derivatives of 2-aminocyclohexanecarboxylic acid (ACHC).

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Bibliographic Details
Published in:Beilstein journal of organic chemistry 2006-05, Vol.2 (1), p.9-9
Main Authors: Masesane, Ishmael B, Batsanov, Andrei S, Howard, Judith A K, Mondal, Raju, Steel, Patrick G
Format: Article
Language:English
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Summary:The nitro oxanorbornene adduct derived from the Diels-Alder reaction of ethyl (E)-3-nitroacrylate and furan provides a versatile template for the stereoselective synthesis of hydroxylated derivatives of 2-aminocyclohexanecarboxylic acid (ACHC).
ISSN:1860-5397
1860-5397
DOI:10.1186/1860-5397-2-9