Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians

Vitamin D plays a pivotal role in the regulation of calcium-phosphorus metabolism, particularly during pediatric age when nutritional rickets and impaired bone mass acquisition may occur.Besides its historical skeletal functions, in the last years it has been demonstrated that vitamin D directly or...

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Published in:Italian journal of pediatrics 2018-05, Vol.44 (1), p.51-51, Article 51
Main Authors: Saggese, Giuseppe, Vierucci, Francesco, Prodam, Flavia, Cardinale, Fabio, Cetin, Irene, Chiappini, Elena, De' Angelis, Gian Luigi, Massari, Maddalena, Miraglia Del Giudice, Emanuele, Miraglia Del Giudice, Michele, Peroni, Diego, Terracciano, Luigi, Agostiniani, Rino, Careddu, Domenico, Ghiglioni, Daniele Giovanni, Bona, Gianni, Di Mauro, Giuseppe, Corsello, Giovanni
Format: Article
Language:English
Subjects:
Adolescent
Adolescents
Child
Child, Preschool
Children
Consensus
Deficiency
Dietary Supplements
Humans
Hypovitaminosis D
Infant
Infant, Newborn
Italy - epidemiology
Review
Societies, Medical
Supplementation
Vitamin D
Vitamin D - physiology
Vitamin D - therapeutic use
Vitamin D Deficiency - complications
Vitamin D Deficiency - epidemiology
Vitamin D Deficiency - prevention & control
Vitamins - therapeutic use
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Summary:Vitamin D plays a pivotal role in the regulation of calcium-phosphorus metabolism, particularly during pediatric age when nutritional rickets and impaired bone mass acquisition may occur.Besides its historical skeletal functions, in the last years it has been demonstrated that vitamin D directly or indirectly regulates up to 1250 genes, playing so-called extraskeletal actions. Indeed, recent data suggest a possible role of vitamin D in the pathogenesis of several pathological conditions, including infectious, allergic and autoimmune diseases. Thus, vitamin D deficiency may affect not only musculoskeletal health but also a potentially wide range of acute and chronic conditions. At present, the prevalence of vitamin D deficiency is high in Italian children and adolescents, and national recommendations on vitamin D supplementation during pediatric age are lacking. An expert panel of the Italian Society of Preventive and Social Pediatrics reviewed available literature focusing on randomized controlled trials of vitamin D supplementation to provide a practical approach to vitamin D supplementation for infants, children and adolescents.
ISSN:1824-7288
1824-7288
DOI:10.1186/s13052-018-0488-7