Nation-Wide Trends in Incidence-Based Mortality of Patients with Ocular Melanoma in USA: 2000 to 2018

Background: Ocular and orbit melanoma is a rare subtype of melanoma for which outcomes have not been adequately reported. We have analyzed the incidence-based mortality trends of ocular and orbit melanoma over 15 years in USA. Most ocular melanomas originate from the uvea and, to a lesser extent, fr...

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Bibliographic Details
Published in:International journal of general medicine 2021-01, Vol.14, p.4171-4176
Main Authors: Valasapalli, Srijan, Guddati, Achuta Kumar
Format: Article
Language:English
Subjects:
Alaska
Analysis
Epidemiology
Immunotherapy
incidence
India
Kinases
Medical imaging
Medical research
Medicine, Experimental
Melanoma
Mortality
Native Americans
ocular melanoma
Original Research
Patient outcomes
trend
Trends
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Summary:Background: Ocular and orbit melanoma is a rare subtype of melanoma for which outcomes have not been adequately reported. We have analyzed the incidence-based mortality trends of ocular and orbit melanoma over 15 years in USA. Most ocular melanomas originate from the uvea and, to a lesser extent, from the conjunctiva. Primary orbital melanoma is exceedingly rare. Methods: The Surveillance, Epidemiology, and End Results (SEER) database was queried to find the incidence-based mortality for all patients diagnosed with ocular and orbit melanoma for the years 2000 to 2018. Results were grouped by gender and race (Caucasian/White, African American/Black, American Indian/Alaskan Native, and Asian/Pacific Islanders). A paired t-test was used to determine the statistically significant difference between various subgroups (p < 0.05). Results: Incidence-based mortality has been the highest in Caucasian/White patients from 2000 to 2018, followed by African American/Black and Asian/Pacific Islander patients. American Indian/Alaskan native patients appear to have the least mortality. There was a statistically significant difference (p
ISSN:1178-7074
1178-7074
DOI:10.2147/IJGM.S299144