Male–female differences following concomitant coronary artery bypass grafting and aortic valve replacement surgery

• Published in: ESC Heart Failure 2024-10, Vol.11 (5), p.2913-2923
• Main Authors: Krey, Rebecca, Jakob, Moritz, Karck, Matthias, Arif, Rawa, Farag, Mina
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Aortic Valve - surgery; Aortic valve replacement; Coronary Artery Bypass - methods; Coronary Artery Disease - surgery; Coronary revascularization; Disparities; Female; Females; Follow-Up Studies; Heart surgery; Heart Valve Prosthesis Implantation - methods; Humans; Kidneys; Male; Male–female differences; Middle Aged; Mortality; Original; Ostomy; Outcome; Postoperative Complications - epidemiology; Retrospective Studies; Risk Factors; Sex Factors; Survival Rate - trends; Variables
• ISSN: 2055-5822; 2055-5822
• DOI: 10.1002/ehf2.14847

Aims Combined coronary artery bypass grafting (CABG) and aortic valve replacement (AVR), and female sex are associated with increased perioperative mortality in clinical risk scores. This study investigated male–female differences in short‐term outcome stratified by age groups. Methods and results All patients undergoing AVR and CABG between January 2001 and June 2021 at our institution were included. 1963 patients were grouped by decades into: 59 years and younger (n = 127), 60–69 (n = 471), 70–79 (n = 1070), and 80 years and older (n = 295). The primary end points of this study were 30 and 180 days mortality. Secondary end points were influence of preoperative risk factors and impact of sex on survival and postoperative major adverse events. Female patients showed higher 30 and 180 days mortality after combined CABG and AVR surgery (8.3% vs. 4.2%, P