An unusual case of Lemierre syndrome – One pathogen or two?

•Lemierre Syndrome is characterized by thrombophlebitis of the internal jugular vein.•The disease is rare, typically preceded by pharyngitis, and is caused usually by Fusobacterium necrophorum.•In rare cases, Lemierre Syndrome is polymicrobial involving other oral microbes. Lemierre syndrome, or sep...

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Bibliographic Details
Published in:IDCases 2021-01, Vol.25, p.e01203, Article e01203
Main Authors: O’Shaughnessy, Michael, Irizarry, Dariel, Finkel, Diana
Format: Article
Language:English
Subjects:
Case Report
Fusobacterium necrophorum
Group C streptococcus
Internal jugular vein thrombophlebitis
Lemierre syndrome
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Summary:•Lemierre Syndrome is characterized by thrombophlebitis of the internal jugular vein.•The disease is rare, typically preceded by pharyngitis, and is caused usually by Fusobacterium necrophorum.•In rare cases, Lemierre Syndrome is polymicrobial involving other oral microbes. Lemierre syndrome, or septic thrombophlebitis of the internal jugular vein, is a rare disease that affects healthy young adults following an episode of pharyngitis or other upper respiratory disease. It most commonly involves the anaerobe Fusobacterium necrophorum, a component of normal oral flora. In this report, we present an unusual case of polymicrobial Lemierre syndrome involving both F. necrophorum and Group C streptococcus following an episode of pharyngitis and streptococcal toxic shock syndrome. Providers should consider the possibility of polymicrobial infection when there are imaging findings suggestive of Lemierre Syndrome and adjust antibiotic regimens accordingly.
ISSN:2214-2509
2214-2509
DOI:10.1016/j.idcr.2021.e01203