Comparison of hybrid coronary revascularization versus coronary artery bypass grafting in patients with multivessel coronary artery disease: a meta-analysis

• Published in: Journal of cardiothoracic surgery 2022-06, Vol.17 (1), p.147-10, Article 147
• Main Authors: Yu, Li, Zhu, Keying, Du, Nannan, Si, Yuexiu, Liang, Jiali, Shen, Ruijing, Chen, Bangsheng
• Format: Article
• Language: English
• Subjects: Angina pectoris; Angioplasty; Bypass; CABG; Cardiac patients; Cardiology; Cardiovascular disease; Cardiovascular diseases; Care and treatment; Clinical trials; Collaboration; Comparative analysis; Coronary artery; Coronary artery bypass; Coronary Artery Bypass - adverse effects; Coronary Artery Disease; Coronary heart disease; Coronary vessels; Grafting; HCR; Health aspects; Heart attacks; Heart diseases; Heart surgery; Humans; MACCE; Meta-analysis; Mortality; MVD; Observational Studies as Topic; Patients; Percutaneous Coronary Intervention - adverse effects; Review; Stents; Stroke; Surgery; Treatment Outcome; Vein & artery diseases; Ventilators
• ISSN: 1749-8090; 1749-8090
• DOI: 10.1186/s13019-022-01903-w

Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are widely used in the treatment of coronary heart disease, but the best revascularization method for multivessel coronary artery disease (MVD) patients is still controversial. Hybrid coronary revascularization (HCR), together with CABG and PCI, have been proved to be feasible methods, but the long-term effect of HCR is not as clear as CABG. By October 2020, we retrieved articles from PubMed, Web of science, EMBASE and Cochrane library databases. The main results are based on major adverse cardiovascular and cerebral events (MACCE). A total of 18 articles (3 randomized controlled trials (RCTs) and 15 observational studies) were included in this meta-analysis. The outcomes of MACCE in the HCR group at perioperative, short-term (30 days to 1 year), medium-term (1 year to 5 years) and long-term (5 years and above) follow-up period were similar to those in the CABG group. The mortality rates of patients in perioperative, short-term and medium-term follow-up were similar to those in the CABG group, but lower than that in the CABG group at long-term follow-up (OR = 0.35, 95% CI 0.18-0.69, p = 0.002). The revascularization rate was higher in the HCR group during the perioperative period (OR = 3.50, 95% CI 2.07-5.94, p