Single-center analysis of patients with frontal fibrosing alopecia: evidence for hypothyroidism and a good quality of life

Objective Frontal fibrosing alopecia (FFA) is an underestimated scarring alopecia. This study aimed to examine epidemiological information, as well as predilection sites, associated diseases, and responses to therapy of patients with FFA. We also aimed to determine whether the extent or duration of...

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Bibliographic Details
Published in:Journal of international medical research 2019-02, Vol.47 (2), p.653-661
Main Authors: Valesky, Eva Maria, Maier, Manuela Denise, Kaufmann, Roland, Zöller, Nadja, Meissner, Markus
Format: Article
Language:English
Subjects:
Aged
Alopecia
Alopecia - drug therapy
Alopecia - epidemiology
Baldness
Clinical Research Reports
Disease Progression
Female
Fibrosis - drug therapy
Fibrosis - epidemiology
Follow-Up Studies
Germany - epidemiology
Humans
Hypothyroidism
Hypothyroidism - physiopathology
Incidence
Prognosis
Quality of Life
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Summary:Objective Frontal fibrosing alopecia (FFA) is an underestimated scarring alopecia. This study aimed to examine epidemiological information, as well as predilection sites, associated diseases, and responses to therapy of patients with FFA. We also aimed to determine whether the extent or duration of disease correlated with the quality of life (QoL). Methods Twelve outpatients with FFA for > 2 years were analyzed. The Erlanger atopic score and the Functional Assessment of Non-life-threatening Conditions (FANLTC) for QoL-assessment were used as scoring systems. Results All patients were women with a mean age of 70.3 years. Most patients did not have any symptoms during their disease progression and no therapy that was used showed any significant effects. FFA was associated with hypothyroidism. There were no correlations between hairline regression, duration of disease, atopic disposition, and QoL. The overall QoL was good. Conclusions The present study shows that there is no correlation between the extent of FFA and QoL or atopic predisposition. There is a strong correlation between the incidence of thyroid disease and FFA.
ISSN:0300-0605
1473-2300
DOI:10.1177/0300060518807335