Malignant transformation of pleomorphic xanthoastrocytoma: case report

We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new oper...

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Bibliographic Details
Published in:Arquivos de neuro-psiquiatria 2003-03, Vol.61 (1), p.104-106
Main Authors: de Tella, Jr, Oswaldo Ignácio, Herculano, Marco Antonio, Prandini, Mirto Nelso, Stavale, João Norberto, Aguiar, Paulo Henrique
Format: Article
Language:English
Subjects:
Adult
astrocytoma
Astrocytoma - pathology
Astrocytoma - surgery
Brain Neoplasms - pathology
Brain Neoplasms - surgery
Cell Transformation, Neoplastic - pathology
Female
Frontal Lobe - pathology
histopathology
Humans
NEUROSCIENCES
PSYCHIATRY
Reoperation
tumor
xanthoastrocytoma
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Summary:We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which revealed a friable tumor, easily differentiated from the normal parenchyma, with cystic components. The histopathological examination demonstrated pleomorphic xanthoastrocytoma with malignant transformation. Histologically, the tumor at first procedure was composed of pleomorphic astrocytes with multinucleated and foamy cells. A rare case of malignant transformation in pleomorphic xanthoastrocytoma is presented, discussed and illustrated in this paper.
ISSN:0004-282X
1678-4227
0004-282X
1678-4227
DOI:10.1590/S0004-282X2003000100020