Persistent middle cerebral artery occlusion associated with lower body temperature on admission

• Published in: Vascular health and risk management 2013-01, Vol.9 (default), p.297-302
• Main Authors: Kvistad, Christopher Elnan, Øygarden, Halvor, Thomassen, Lars, Waje-Andreassen, Ulrike, Naess, Halvor
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Angiography; Biomarkers - blood; Body temperature; Body Temperature Regulation; Cerebral Angiography - methods; Cerebrovascular disease; clot lysis; CT imaging; Diagnosis; Female; Humans; Infarction, Middle Cerebral Artery - blood; Infarction, Middle Cerebral Artery - diagnosis; Infarction, Middle Cerebral Artery - physiopathology; ischemic stroke; Logistic Models; Male; MCA occlusion; Medical imaging; Middle Aged; Multivariate Analysis; Norway; Odds Ratio; Original Research; Patient Admission; Physiological aspects; Predictive Value of Tests; Prognosis; Prospective Studies; Registries; Stroke; Tomography, X-Ray Computed
• ISSN: 1178-2048; 1176-6344; 1178-2048
• DOI: 10.2147/VHRM.S44570

Low body temperature is considered neuroprotective in ischemic stroke, yet some studies suggest that low body temperature may also inhibit clot lysis and recanalization. We hypothesized that low body temperature was associated with persistent proximal middle cerebral artery (MCA) occlusion in patients with acute ischemic stroke presenting with symptoms of proximal MCA occlusion, suggesting a possible detrimental effect of low body temperature on recanalization. All patients with acute ischemic stroke admitted to our Stroke Unit between February 2006 and August 2012 were prospectively registered in a database. Computed tomography (CT) angiography was performed in patients admitted