Impact of acute stress on cortical electrical activity and cardiac autonomic coupling

• Published in: Journal of integrative neuroscience 2020-06, Vol.19 (2), p.239-248
• Main Authors: Chalmers, Taryn, Maharaj, Shamona, Lees, Ty, Lin, C T, Newton, Phillip, Clifton-Bligh, Roderick, McLachlan, Craig S, Gustin, Sylvia M, Lal, Sara
• Format: Article
• Language: English
• Subjects: Adult; Delta Rhythm - physiology; Electrocardiography; electrocardiography|electroencephalography|heart rate variability|occupational stress|stress|nursing|cardiac|neuroscience|neural-cardiac coupling|psychophysiology; Female; Gamma Rhythm - physiology; Heart Rate - physiology; Humans; Male; Parasympathetic Nervous System - physiology; Prefrontal Cortex - physiology; Stress, Psychological - physiopathology; Young Adult
• ISSN: 0219-6352; 1757-448X
• DOI: 10.31083/j.jin.2020.02.74

Assessment of heart rate variability (reflective of the cardiac autonomic nervous system) has shown some predictive power for stress. Further, the predictive power of the distinct patterns of cortical brain activity and - cardiac autonomic interactions are yet to be explored in the context of acute stress, as assessed by an electrocardiogram and electroencephalogram. The present study identified distinct patterns of neural-cardiac autonomic coupling during both resting and acute stress states. In particular, during the stress task, frontal delta waves activity was positively associated with low-frequency heart rate variability and negatively associated with high-frequency heart rate variability. Low high-frequency power is associated with stress and anxiety and reduced vagal control. A positive association between resting high-frequency heart rate variability and frontocentral gamma activity was found, with a direct inverse relationship of low-frequency heart rate variability and gamma wave coupling at rest. During the stress task, low-frequency heart rate variability was positively associated with frontal delta activity. That is, the parasympathetic nervous system is reduced during a stress task, whereas frontal delta wave activity is increased. Our findings suggest an association between cardiac parasympathetic nervous system activity and frontocentral gamma and delta activity at rest and during acute stress. This suggests that parasympathetic activity is decreased during acute stress, and this is coupled with neuronal cortical prefrontal activity. The distinct patterns of neural-cardiac coupling identified in this study provide a unique insight into the dynamic associations between brain and heart function during both resting and acute stress states.