Increased eating control and energy levels associated with consumption of bitter orange ( p -synephrine) extract: a randomized placebo-controlled study

Using a placebo-controlled double-blinded 30-day protocol, 40 overweight adults were asked to consume a chocolate-flavored chew 15-30 min before their two largest meals of the day. The chews contained either a placebo or an "active" product (100 mg of a bitter orange extract, standardized...

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Bibliographic Details
Published in:Nutrition and dietary supplements 2017-01, Vol.9, p.29-35
Main Authors: Kaats, Gilbert R, Leckie, Robert B, Mrvichin, Nate, Stohs, Sidney J
Format: Article
Language:English
Subjects:
Adipocytes
Alkaloids
Appetite
Appetite depressants
appetite suppression
Bitter orange
Bitter orange extract
Blood
Caffeine
Citrus aurantium
Citrus fruits
Composition
Dietary supplements
energy
Health aspects
Medical research
Metabolism
Oxidation
p-synephrine
safety
Studies
Weight control
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Summary:Using a placebo-controlled double-blinded 30-day protocol, 40 overweight adults were asked to consume a chocolate-flavored chew 15-30 min before their two largest meals of the day. The chews contained either a placebo or an "active" product (100 mg of a bitter orange extract, standardized to 51.5 mg p-synephrine). Subjects completed a 13-item Weight Control Support Scale (WCSS) containing eating control, energy level, and palatability subscales daily throughout the study. All 40 subjects completed the study. No adverse effects were reported in either the placebo or active groups. As compared to placebo, subjects consuming the active product reported statistically more (p[less than or equal to]0.001) positive responses on the WCSS as well as on each of the three subscales. This study suggests that, as compared to a placebo control, consuming a chew containing bitter orange extract (51.5 mg p-synephrine) 15-30 min before the two largest meals of the day resulted in a statistically significant greater and more positive response to eating/appetite control and a weight-control support scale. Keywords: bitter orange extract, p-synephrine, Citrus aurantium, appetite suppression, energy, safety
ISSN:1179-1489
1179-1489
DOI:10.2147/NDS.S136756