Clinical and morphological effects of hyperbaric oxygen therapy in patients with interstitial cystitis associated with fibromyalgia

Interstitial Cystitis (IC) is a debilitating disorder of the bladder, with a multifactorial and poorly understood origin dealing with microcirculation repeated damages. Also Fibromyalgia (FM) is a persistent disorder whose etiology is not completely explained, and its theorized alteration of pain pr...

Full description

Saved in:
Bibliographic Details
Published in:BMC urology 2019-11, Vol.19 (1), p.108-108, Article 108
Main Authors: Bosco, Gerardo, Ostardo, Edoardo, Rizzato, Alex, Garetto, Giacomo, Paganini, Matteo, Melloni, Giorgio, Giron, Giampiero, Pietrosanti, Lodovico, Martinelli, Ivo, Camporesi, Enrico
Format: Article
Language:English
Subjects:
Aged
Care and treatment
Clinical trials
Cystitis
Cystitis, Interstitial - complications
Cystitis, Interstitial - pathology
Cystitis, Interstitial - therapy
Cystoscopy
Development and progression
Etiology (Medicine)
Female
Fibromyalgia
Fibromyalgia - complications
Fibromyalgia - pathology
Fibromyalgia - therapy
Health aspects
Humans
Hyperbaric medicine
Hyperbaric Oxygenation
Interstitial cystitis
Male
Middle Aged
Purpura
Quality of Life
Ulcers
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Interstitial Cystitis (IC) is a debilitating disorder of the bladder, with a multifactorial and poorly understood origin dealing with microcirculation repeated damages. Also Fibromyalgia (FM) is a persistent disorder whose etiology is not completely explained, and its theorized alteration of pain processing can compromise the quality of life. Both these conditions have a high incidence of conventional therapeutic failure, but recent literature suggests a significant beneficial response to Hyperbaric Oxygen Therapy (HBOT). With this study, this study we evaluated the effects of HBOT on quality of life, symptoms, urodynamic parameters, and cystoscopic examination of patients suffering from both IC and FM. We structured an observational clinical trial design with repeated measures (questionnaires, urodynamic test, and cystoscopy) conducted before and 6 months after a therapeutic protocol with hyperbaric oxygen for the treatment of patients suffering from both IC and FM. Patients were exposed to breathing 100% oxygen at 2 atm absolute (ATA) in a multiplace pressure chamber for 90 min using an oro-nasal mask. Patients undertook a cycle of 20 sessions for 5 days per week, and a second cycle of 20 sessions after 1 week of suspension. Twelve patients completed the protocol. Changes after HBOT were not significant, except for hydrodistension tolerance (mean pre-treatment: 409.2 ml; mean post-treatment: 489.2 ml; p 
ISSN:1471-2490
1471-2490
DOI:10.1186/s12894-019-0545-6