Acute kidney injury following supine mini-PNL versus retrograde intrarenal surgery in patients with renal stones < 3 cm: a prospective comparative study

Background The purpose of the current study was to prospectively compare mini-PNL and RIRS for development of acute kidney injury (AKI), success, and complication rates in a cohort of patients with kidney stones less than 3 cm. Methods In this prospective study, data of 60 consecutive patients under...

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Bibliographic Details
Published in:African journal of urology 2020-12, Vol.26 (1), p.42-5, Article 42
Main Authors: Yığman, Metin, Tangal, Semih, Candar, Tuba, Gökçe, Mehmet İlker
Format: Article
Language:English
Subjects:
Acute kidney injury
Biomarkers
Care and treatment
Comparative analysis
Complications and side effects
Creatinine
Gender
Hospitalization
Imaging
Kidney stones
Kidneys
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
NGAL
Original Research
Percutaneous nephrolithotomy
Radiology
Retrograde intrarenal surgery
Sample size
Statistical analysis
Surgery
Urine
Urology
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Summary:Background The purpose of the current study was to prospectively compare mini-PNL and RIRS for development of acute kidney injury (AKI), success, and complication rates in a cohort of patients with kidney stones less than 3 cm. Methods In this prospective study, data of 60 consecutive patients underwent mini-PNL ( n  = 31) or RIRS ( n  = 29) was investigated. Urinary NGAL levels were measured preoperatively and at postoperative 6th hour to evaluate AKI. Success and complication rates were also compared. Results The mean stone size was significantly higher in the mini-PNL group (24.6 mm vs. 18.2 mm, p  = 0.02). The mean postoperative NGAL levels were 45.6 ± 12.4 and 48.1 ± 13.6 for the mini-PNL and RIRS groups, respectively. The increase was statistically significant for both groups ( p : 0.01). The difference between the two groups for mean postoperative NGAL measurements was not statistically significant ( p  = 0.47). The SFR was significantly higher in the mini-PNL group (96.7% vs. 79.3%, p  = 0.04). The complication rates were similar for the two groups ( p  = 0.99). The mean duration of operation was 48.2 ± 22.5 min in the mini-PNL group and 62.6 ± 18.1 min in the RIRS group ( p  = 0.03). The median duration of hospitalization was 1 day for both groups. Conclusions In patients with renal stones 
ISSN:1110-5704
1961-9987
DOI:10.1186/s12301-020-00052-7