Impact of Voluntary Folic Acid Fortification of Corn Masa Flour on RBC Folate Concentrations in the U.S. (NHANES 2011-2018)

Surveillance data have highlighted continued disparities in neural tube defects (NTDs) by race-ethnicity in the United States. Starting in 2016, the Food and Drug Administration (FDA) authorized voluntary folic acid fortification of corn masa flour to reduce the risk of neural tube defects (NTDs) am...

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Bibliographic Details
Published in:Nutrients 2021-04, Vol.13 (4), p.1325
Main Authors: Wang, Arick, Rose, Charles E, Qi, Yan Ping, Williams, Jennifer L, Pfeiffer, Christine M, Crider, Krista S
Format: Article
Language:English
Subjects:
Acculturation
Acids
Age
Birth defects
Cereals
Corn
corn masa
Crystal defects
Education
Erythrocytes
Flour
Folic acid
Food fortification
Food intake
Fortified foods
Hispanic Americans
Households
Interviews
Masa
Minority & ethnic groups
Neural tube defects
NTDs
Nutrition
Ratios
Response rates
Risk
Risk reduction
Vegetables
Vitamin B
Womens health
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Summary:Surveillance data have highlighted continued disparities in neural tube defects (NTDs) by race-ethnicity in the United States. Starting in 2016, the Food and Drug Administration (FDA) authorized voluntary folic acid fortification of corn masa flour to reduce the risk of neural tube defects (NTDs) among infants of Hispanic women of reproductive age. To assess the impact of voluntary corn masa fortification, cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) 2011-2018 for Hispanic women of reproductive age with available red blood cell (RBC) folate concentrations were analyzed, with additional analyses conducted among Hispanic women whose sole source of folic acid intake was fortified foods (enriched cereal grain products (ECGP) only), excluding ready-to-eat cereals and supplements. RBC folate concentration (adjusted geometric mean) among Hispanic women of reproductive age did not differ between 2011-2016 and 2017-2018, though RBC folate concentration increased significantly among lesser acculturated Hispanic women consuming ECGP only. Concentrations of RBC folate for those born outside the U.S and residing in the U.S
ISSN:2072-6643
2072-6643
DOI:10.3390/nu13041325