Advanced Medical Devices for Preparation and Administration of Chemotherapeutic Agents: Results from a Multi-Dimensional Evaluation

To evaluate the incremental benefits concerning the implementation of closed-system medical devices for the preparation and administration of chemotherapy agents (integrated or not with traceable workflow), within an Italian clinical practice, in which the use of such technologies is not standardize...

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Bibliographic Details
Published in:ClinicoEconomics and outcomes research 2020-01, Vol.12, p.711-722
Main Authors: Ferrario, Lucrezia, Schettini, Fabrizio, Garagiola, Elisabetta, Cecchi, Adriana, Lugoboni, Lucia, Serra, Paolo, Porazzi, Emanuele, Foglia, Emanuela
Format: Article
Language:English
Subjects:
Analysis
Cancer therapies
Chemotherapy
chemotherapy agents
closed-system medical device
Cytotoxicity
Drug dosages
economic evaluation
Hospitals
hta
Literature reviews
Medical equipment
Nurses
organisational benefits
Original Research
Patient safety
Pharmacists
Prevention
Professionals
safety
Safety and security measures
Workflow software
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Summary:To evaluate the incremental benefits concerning the implementation of closed-system medical devices for the preparation and administration of chemotherapy agents (integrated or not with traceable workflow), within an Italian clinical practice, in which the use of such technologies is not standardized. Four Scenarios, implying different levels of technologies introduction, were analyzed, based on the presence and/or absence of closed systems and traceable workflow, in the preparation and in the administration phase. A literature review was conducted, in order to retrieve efficacy and safety measures. Economic and organizational benefits, assuming a hospitals perspective, were assessed by means of health-economics tools, considering 27,660 (±695.86) drugs on average prepared, on an annual basis, by 12 hospitals involved. The typology of medical devices and other devices/equipment used, the human resources involved, and the time spent for the preparation and administration phases were collected. Literature stated that the introduction of advanced technologies (CSTDs in the preparation phase, closed-system in the administration phase, both integrated by a traceable workflow) could: i) decrease surface contamination (12.24% vs 26.39%,
ISSN:1178-6981
1178-6981
DOI:10.2147/CEOR.S267283