The body weight change during the first year of HEMODIALYSIS IS a strong predictor of patient survival

• Published in: Kidney research and clinical practice 2012-06, Vol.31 (2), p.A23-A24
• Main Authors: Chazot, Charles, Deleaval, Patrik, Bernollin, Anne-Lise, Vo-Van, Cyril, Jean, Guillaume
• Format: Article
• Language: English
• Subjects: Nephrology
• ISSN: 2211-9132
• DOI: 10.1016/j.krcp.2012.04.355

Hemodialysis patients are exposed to a high risk of death. We report the influence of the body weight (BW) change (Δ) on the survival in an incident HD patient cohort.Between January 2000 to 2009, 251 patients (age=65,8±14,8 y.o.; F/M=93/158; diabetes=36%) survived at least one year after HD onset and were followed for 44,9 months. The prescribed BW decreased by 6.5±5% at Week 8 (W8) and then increased again. From W8 to W52, the BW Δ was+1,9±7,4%. According to the median of W52-W8 BW Δ (+2.35%), the Kaplan Meier analysis (see figure below) displayed a significant better survival in patients with a BW Δ above the median. These two groups were not different according to age, diabetes or cardiovascular event history but had a significant higher interdialytic weight gain and protein intake. In the Cox model analysis the patient overall mortality was related to age (p