Inflammatory indicator levels in patients undergoing aortic valve replacement via median sternotomy with preoperative anxiety and postoperative complications: a prospective cohort study

Objective This study was performed to evaluate the association of preoperative anxiety with inflammatory indicators and postoperative complications in patients undergoing scheduled aortic valve replacement surgery. Methods A prospective cohort study was performed. The Hamilton Anxiety Scale was used...

Full description

Saved in:
Bibliographic Details
Published in:Journal of international medical research 2021-02, Vol.49 (2), p.300060520977417-300060520977417
Main Authors: Gao, Qiang, Mok, Hsiao-Pei, Zhang, Hong-Yu, Qiu, Hai-Long, Liu, Jian, Chen, Ze-Rui, Teng, Yun, Li, Xiao-Hua, Cen, Jian-Zheng, Chen, Ji-Mei, Zhuang, Jian
Format: Article
Language:English
Subjects:
Anxiety
Anxiety - etiology
Aortic Valve - surgery
Cohort analysis
Heart surgery
Heart Valve Prosthesis Implantation - adverse effects
Humans
Inflammation
Postoperative Complications - etiology
Prospective Clinical Research Report
Prospective Studies
Sternotomy
Surgical outcomes
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective This study was performed to evaluate the association of preoperative anxiety with inflammatory indicators and postoperative complications in patients undergoing scheduled aortic valve replacement surgery. Methods A prospective cohort study was performed. The Hamilton Anxiety Scale was used to assess preoperative anxiety. The serum white blood cell (WBC) count and concentrations of C-reactive protein, interleukin (IL)-6, and IL-8 were measured 1 day preoperatively and 3 and 7 days postoperatively. Postoperative complications were also recorded. Results Seventy-three patients were included. The incidence of preoperative anxiety was 30.1% (22/73). The payment source was the only independent risk factor for preoperative anxiety. The incidence of postoperative complications was lowest in the mild anxiety group. The WBC count 3 days postoperatively was significantly lower in the mild than moderate-severe anxiety group. The IL-8 concentration 1 day preoperatively was highest in the no anxiety group. Conclusions Mild preoperative anxiety might help to improve clinical outcomes. However, further investigations with more patients are warranted. Patients with different degrees of anxiety may have different levels of inflammatory cytokines.
ISSN:0300-0605
1473-2300
DOI:10.1177/0300060520977417