Frequency of frailty and its association with cognitive status and survival in older Chileans

Age-associated brain physiologic decline and reduced mobility are key elements of increased age-associated vulnerability. To study the frequency of frailty phenotype and its association with mental health and survival in older Chileans. Follow-up of ALEXANDROS cohorts designed to study disability as...

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Bibliographic Details
Published in:Clinical interventions in aging 2017-01, Vol.12, p.995-1001
Main Authors: Albala, Cecilia, Lera, Lydia, Sanchez, Hugo, Angel, Barbara, Márquez, Carlos, Arroyo, Patricia, Fuentes, Patricio
Format: Article
Language:English
Subjects:
Age
Aged
Aged, 80 and over
Aging
Chile
Chile - epidemiology
Cognitive ability
Cognitive disorders
Cognitive Dysfunction - epidemiology
Cognitive Impairment
Complications and side effects
Dementia
Depression (Mood disorder)
Fatigue - epidemiology
Female
Frail elderly
Frail Elderly - statistics & numerical data
Frailty
Frailty - epidemiology
Genotype & phenotype
Geriatric Assessment
Geriatrics
Hand Strength
Health care policy
Humans
Life expectancy
Logistic Models
Male
Mental depression
Middle Aged
Mobility Limitation
Mortality
Nutrition
Obesity - epidemiology
Odds Ratio
Older people
Original Research
Patient outcomes
Population
Prevalence
Risk Factors
Statistics
Walking
Weight control
Womens health
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Description
Summary:Age-associated brain physiologic decline and reduced mobility are key elements of increased age-associated vulnerability. To study the frequency of frailty phenotype and its association with mental health and survival in older Chileans. Follow-up of ALEXANDROS cohorts designed to study disability associated with obesity in community-dwelling people 60 years and older living in Santiago, Chile. At baseline, 2,098 (67% women) of 2,372 participants had the necessary measurements for the identification of the frailty phenotype: weak handgrip dynamometry, unintentional weight loss, fatigue/exhaustion, five chair-stands/slow walking speed and difficulty walking (low physical activity). After 10-15 years, 1,298 people were evaluated and 373 had died. Information regarding deaths was available for the whole sample. The prevalence of frailty at baseline (≥3 criteria) in the whole sample was 13.9% (women 16.4%; men 8.7%) and the pre-frailty prevalence (1-2 criteria) was 63.8% (65.0% vs 61.4%), respectively. Frailty was associated with cognitive impairment (frail 48.1%; pre-frail 21.7%; nonfrail 20.5%,
ISSN:1178-1998
1176-9092
1178-1998
DOI:10.2147/CIA.S136906