SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma

Platelet-rich plasma (PRP) is a rising therapy treating locomotor system lesions such as knee osteoarthritis. The objective of this study was to evaluate patients’ satisfaction 6 to 12 months after a PRP injection for cartilage lesions of their knee under real-life conditions. Patients’ satisfaction...

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Bibliographic Details
Published in:Bioengineering (Basel) 2023-11, Vol.10 (11), p.1276
Main Authors: Verron, Romain, Zhang, Lucie, Bisseriex, Hélène, Grimandi, Ronan, Verrando, Alix, Verdaguer, Claire, Thomas, Marie, Facione, Julia, Borrini, Leo
Format: Article
Language:English
Subjects:
Arthritis
Bioengineering
Blood platelets
Cartilage
Cartilage diseases
Criteria
Evaluation
Injection
Injuries
intra-articular injection
Knee
Lesions
Osteoarthritis
Pain
Patient satisfaction
Plasma
platelet-rich plasma
Platelets
Questionnaires
SATMED-Q
Statistical analysis
Steroids
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Summary:Platelet-rich plasma (PRP) is a rising therapy treating locomotor system lesions such as knee osteoarthritis. The objective of this study was to evaluate patients’ satisfaction 6 to 12 months after a PRP injection for cartilage lesions of their knee under real-life conditions. Patients’ satisfaction was assessed by a specific questionnaire named SATMED-Q©, which explores six different dimensions of a given treatment. In addition, pain and function were assessed thanks to VAS pain, WOMAC, and IKDC scores. Responders were identified through the OMERACT-OARSI criteria. We observed excellent satisfaction after a PRP injection with a SATMED-Q© score of 80.81% 6 to 12 months after the procedure. Even when there was no significant improvement in pain and function scores, 52% of the evaluated population fulfilled the OMERACT-OARSI criteria and were considered responders. According to the sub-group analysis, patients with less osteoarthritis damage (i.e., Kellgren–Lawrence grades 1–2) and older study subjects (i.e., >40 years old) with focal chondropathy had benefited most from their PRP injection. Thus, platelet-rich plasma seems to be a well-tolerated and efficient therapy for cartilage lesions of the knee.
ISSN:2306-5354
2306-5354
DOI:10.3390/bioengineering10111276