Transcutaneous cervical vagus nerve stimulation improved motor cortex excitability in healthy adults: a randomized, single-blind, self-crossover design study

Purpose: To investigate the effect of transcutaneous cervical vagus nerve stimulation (tcVNS) on motor cortex excitability in healthy adults.Method: Twenty eight healthy subjects were assigned to receive real and sham tcVNS for 30 minutes. The interval between the real and sham conditions was more t...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in neuroscience 2023-10, Vol.17, p.1234033-1234033
Main Authors: Wang, Meng-Xin, Wumiti, Aihaiti, Zhang, Yao-Wen, Gao, Xue-Sheng, Huang, Zi, Zhang, Meng-Fei, Peng, Zhi-Yong, Oku, Yoshitaka, Tang, Zhi-Ming
Format: Article
Language:English
Subjects:
Cortex (motor)
Electrodes
Excitability
Latency
Magnetic fields
Medical research
motor cortex excitability
motor evoke potential
Motor evoked potentials
neuromodulation
Neuroscience
noninvasive vagus nerve stimulation
Rehabilitation
Skin
Stroke
Transcranial magnetic stimulation
Vagus nerve
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose: To investigate the effect of transcutaneous cervical vagus nerve stimulation (tcVNS) on motor cortex excitability in healthy adults.Method: Twenty eight healthy subjects were assigned to receive real and sham tcVNS for 30 minutes. The interval between the real and sham conditions was more than 24 hours, and the sequence was random. The central and peripheral motor-evoked potential (MEP) of the right first dorsal interosseous (FDI) muscle was measured by transcranial magnetic stimulation (TMS) before and after stimulation. MEP latency, MEP amplitude and rest motor threshold (rMT) were analyzed before and after stimulation.Results: MEP amplitude, MEP latency and rMT had significant interaction effect between time points and conditions (p0.05).Conclusion: tcVNS could improve motor cortex excitability in healthy adults.
ISSN:1662-453X
1662-4548
1662-453X
DOI:10.3389/fnins.2023.1234033