Viral metagenomic survey of Caspian seals

Viral diseases of pinnipeds cause substantial mortality and morbidity and can influence population demography. Viral metagenomic studies can therefore play an important role in pinniped health assessments and disease surveillance relevant to both individual species and in a "One Health" co...

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Bibliographic Details
Published in:Frontiers in veterinary science 2024-09, Vol.11, p.1461135
Main Authors: Karamendin, Kobey, Goodman, Simon J, Kasymbekov, Yermukhammet, Kumar, Marat, Nuralibekov, Sardor, Kydyrmanov, Aidyn
Format: Article
Language:English
Subjects:
Caspian seal
marine mammals
pinniped
Pusa caspica
Veterinary Science
viral metagenome
virome
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Summary:Viral diseases of pinnipeds cause substantial mortality and morbidity and can influence population demography. Viral metagenomic studies can therefore play an important role in pinniped health assessments and disease surveillance relevant to both individual species and in a "One Health" context. This study used a metagenomic approach with high throughput sequencing to make the first assessment of viral diversity in Caspian seals ( ), the only marine mammal species endemic to the Caspian Sea. Sequencing libraries from 35 seals sampled 2009-2020 were analysed, finding sequences from the viral families and with additional detection of via PCR. The similarity of viral contigs from Caspian seal to sequences recovered from other pinnipeds ranged from 63.74% (San Miguel sea lion calicivirus) to 78.79% (Seal anellovirus 4). Some findings represent novel viral species, but overall, the viral repertoire of Caspian seals is similar to available viromes from other pinnipeds. Among the sequences recovered were partial contigs for influenza B, representing only the second such molecular identification in marine mammals. This work provides a foundation for further studies of viral communities in Caspian seals, the diversity of viromes in pinnipeds more generally, and contributes data relevant for disease risk assessments in marine mammals.
ISSN:2297-1769
2297-1769
DOI:10.3389/fvets.2024.1461135