A High-Resolution MRI Study of Relationship between Remodeling Patterns and Ischemic Stroke in Patients with Atherosclerotic Middle Cerebral Artery Stenosis

Recently, high-resolution magnetic resonance imaging (HR-MRI) has been used to depict the wall characteristics of the intracranial arteries. The aim of this study was to explain the relationship between the remodeling patterns and acute ischemic stroke in patients with atherosclerotic middle cerebra...

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Bibliographic Details
Published in:Frontiers in aging neuroscience 2017-05, Vol.9, p.140-140
Main Authors: Zhang, Dan-Feng, Chen, Yu-Chen, Chen, Huiyou, Zhang, Wei-Dong, Sun, Jun, Mao, Cun-Nan, Su, Wen, Wang, Peng, Yin, Xindao
Format: Article
Language:English
Subjects:
Angiography
Arteriosclerosis
Atherosclerosis
high-resolution MRI
Ischemia
ischemic stroke
Magnetic resonance imaging
Medical imaging
middle cerebral artery stenosis
Neuroscience
NMR
Nuclear magnetic resonance
remodeling pattern
Stenosis
Stents
Veins & arteries
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Summary:Recently, high-resolution magnetic resonance imaging (HR-MRI) has been used to depict the wall characteristics of the intracranial arteries. The aim of this study was to explain the relationship between the remodeling patterns and acute ischemic stroke in patients with atherosclerotic middle cerebral artery (MCA) stenosis using HR-MRI. From August 2015 to May 2016, we prospectively screened 33 consecutive patients with unilateral MCA stenosis using time-to-flight MR angiography, including 15 patients with symptomatic MCA stenosis and 18 patients with asymptomatic MCA stenosis. Among them, 14 patients were diagnosed as positive remodeling (PR) and 19 as negative remodeling or non-remodeling. The cross-sectional images of the stenotic MCA wall on HR-MRI including T1WI, T2WI, and PDWI were compared between the symptomatic group and the asymptomatic group as well as the PR group and the non-PR group, based on the vessel area, lumen area, wall area, plaque area, degree of stenosis, remodeling index, and NIHSS score. The symptomatic group had larger wall area ( = 0.040), plaque area (
ISSN:1663-4365
1663-4365
DOI:10.3389/fnagi.2017.00140