Association of chorioretinal thickness with chronic kidney disease

• Published in: BMC ophthalmology 2023-02, Vol.23 (1), p.55-55, Article 55
• Main Authors: Basiony, Ahmed Ibrahim, Atta, Sherry Nissem, Dewidar, Noha Mohamed, Zaky, Adel Galal
• Format: Article
• Language: English
• Subjects: Blood; C-reactive protein; Choroid; Chronic kidney disease; Chronic kidney failure; Creatinine; Cross-Sectional Studies; Diabetic retinopathy; Epidermal growth factor receptors; Eye; Eye diseases; Glomerular filtration rate; Hemodialysis; Humans; Kidney diseases; Ophthalmology; Optical coherence tomography; Proteinuria; Renal Insufficiency, Chronic - complications; Renal Insufficiency, Chronic - diagnosis; Renal replacement therapy; Retina; Retinal Degeneration; Retinal nerve fiber layer; Tomography, Optical Coherence - methods; Variance analysis
• ISSN: 1471-2415; 1471-2415
• DOI: 10.1186/s12886-023-02802-x

To assess retinal and choroidal thickness changes in chronic kidney disease (CKD) patients using spectral domain optical coherence tomography (SD-OCT). CKD is a devastating health trouble. The eye and the kidney share similar structural and genetic pathways, so that kidney disease and ocular disease may be closely linked. OCT is a precise, fast method for high-definition scanning of the retina and choroid. A cross sectional study was conducted at Menoufia University Hospital ophthalmology department on 144 eyes of 72 CKD patients divided into 3 groups according to the stage of CKD as follows: group 1: CKD stage 1-2, with Glomerular Filtration Rate (GFR) > 60 ml/min/1.73m group 2: CKD stage 3, GFR 30-59 ml/min/1.73m and group 3: CKD stage 4-5, eGFR