Sex and age differences in mortality trends of gastric cancer among Hispanic/Latino populations in the United States, Latin America, and the Caribbean

• Published in: Lancet Regional Health - Americas (Online) 2022-12, Vol.16, p.100376-100376, Article 100376
• Main Authors: Torres-Roman, J. Smith, Alvarez, Christian S., Guerra-Canchari, Pedro, Valcarcel, Bryan, Martinez-Herrera, José Fabián, Dávila-Hernández, Carlos A., Santos, Camila Alves, Soares, Samara Carollyne Mafra, de Souza, Dyego Leandro Bezerra, Camargo, M. Constanza
• Format: Article
• Language: English
• Subjects: Gastric cancer; Hispanics; Latinos; Mortality trends
• ISSN: 2667-193X; 2667-193X
• DOI: 10.1016/j.lana.2022.100376

An up-to-date analysis of gastric cancer mortality among Hispanic/Latino populations is required for estimating disease burden and assessing the effectiveness of clinical and preventive strategies. We retrieved gastric cancer deaths between 1997 and 2017 (as available) from the Surveillance, Epidemiology, and End Results Program (United States Hispanics) and the World Health Organization databases (Puerto Rico, 16 Latin American and Caribbean countries). Joinpoint regression analysis was used to examine trends in age-standardized mortality rates (ASMR; per 100 000 person-years) and calculate average annual percent changes (AAPCs) by country (or territory), age group (25–49 and ≥50 years), and sex. Trends were compared to assess slope parallelism. In 2017, Chile (31·8), Colombia (24·3) and Costa Rica (24·3) had the highest ASMR of gastric cancer for men, while Guatemala (17·2), Peru (13·5), and Costa Rica (13·3) had the highest ASMR for women. Small-to-moderate mortality declines (AAPCs ranged −4 to −0.5%) were observed between 1997 and 2017. In almost all countries, trends decreased among individuals aged ≥50 years. However, age-specific trends were not parallel (p-values